Endocrine Abstracts

Introduction: Premature ovarian failure (POF) is defined as amenorrhea lasting more than four months before the age of 40 with a high level of gonadotropins in at least two separate samples. The aim of this work was to describe the etiological profile of a series of Tunisian women followed for POF.Patients and methods: It is a descriptive study of 42 cases of POF collected in the endocrinology department of Sousse between 2000 and 2017.<p class="abst...

Background: Amputation is the major complication of diabetic foot. The aims of our study were to assess prevalence of amputation in a group of long-standing type 1 diabetic patients and to determine its risk factors.Methods: We conducted a cross-sectional study including type 1 diabetic patients followed at the National Institute of Nutrition of Tunis. All patients had a duration of diabetes ≥ 20 years. Clinical and biological data were collected f...

Background: While sexual dysfunction in men with type 1 diabetes is well known, sexual dysfunction in women remains a neglected issue. The aim of this study was to assess the sexual quality of life (SQOL) of women with long-standing type 1 diabetes.Methods: We conducted a cross-sectional study of women followed at the National Institute of Nutrition and Food Technology of Tunis. We included women with type 1 diabetes for 20 years or more. Women who were ...

Background: Long-standing type 1 diabetes, had many complications which have an impact on both life expectancy and quality of life of these patients. The aims of our study were to evaluate the quality of life of a group of Tunisian patients with type 1 diabetes evolving for more than 20 years as well as to determine the factors associated with its alteration.Methods: We conducted a descriptive observational cross-sectional study including type 1 diabetic...

Background: Erectile dysfunction impairs the quality of life of men with type 1 diabetes. Many factors are involved in this complication. According to the literature, diabetic microangiopathy is associated with erectile dysfunction. The aim of our study was to evaluate the impact of diabetic retinopathy on erectile dysfunction in a group of long-standing type 1 diabetics.Methods: We conducted a cross-sectional study that included male patients with type ...

Introduction: 11-Beta-hydroxylase deficiency (11β-OHD) is the second most common cause of congenital adrenal hyperplasia. It leads to the accumulation of steroids precursors prior to the enzyme defect, notably 11-deoxycorticosterone (DOC), leading therefore to low renin hypertension and hypokalemia. Hence, patients with 11β-OHD are reportedly protected from adrenal crisis. Here, we report a case of a male with 11β-OHD presenting with acute adrenal insufficiency....

Objective: Dyslipidemia represents an added factor of cardiovascular risk for patients with diabetes. The objective of this work was to study the characteristics of dyslipidemia in a group of patients with diabetes.Methods Cross-sectional study including a group of patients with diabetes associated with dyslipidemia, during a period of 6 months, admitted in the day hospital unit of the National Institute of Nutrition of Tunis. The data was collected by c...

Introduction: Female sexual dysfunction (FSD) is a frequent comorbidity in women with type 2 diabetes mellitus (T2DM), and is now increasingly considered a surrogate marker of endothelial dysfunction as well as a sentinel predictor of new-onset macroangiopathic events. Less attention, however, has been directed at the potential association of FSD and microangiopathy in hyperglycemic states.Methods: We analyzed 30 consecutive female T2DM outpatients in wh...

Introduction: Sexuality can include several dimensions such as thoughts, fantasies, desires, beliefs\.. But these can be influenced by biological, psychological, socio-economic factors or somatic pathologies, such as diabetes. The aim of our study was to evaluate the sexuality of women with type 2 diabetes mellitus and its different dimensions, as well as the predictive factors of female sexual dysfunction (FSD) among this population.Methods: This is a c...

Introduction: Pituitary insufficiency is a late-onset sequel of cranial irradiation for nasopharyngeal tumors. In a Cancer Survivor Study, 43% of patients treated for nasopharyngeal tumors had one or more endocrinopathies. We aim to characterize the pituitary-related outcomes following cranial radiotherapy for nasopharyngeal tumors over a period of 5 years.Material and methods: The effects of cranial irradiation on hypothalamic-pituitary function were st...